Scientists studying skin and breast cancer in genetically modified mice have spotted hybrid cancer cells that combine the properties of different cell types, a discovery that could help understand how cancer spreads in the body and provide a new target for treatment.
The big data explosion, which allows scientists to analyse factors such as people’s lifestyles, genes and medical records to develop personalised treatments for conditions, has so far mostly benefitted rare diseases with simple causes. But now, complex problems such as cardiovascular disease and dementia are getting the big data treatment.
In 1984, after HIV was identified as the cause of AIDS, the US secretary of health, Margaret Heckler, declared a vaccine would be found within two years. Reports of a mysterious virus predominantly affecting gay men had been growing across the US and, with awareness rising, the World Health Organization had held its first conference to address the global situation earlier that year. But there was still little understanding of how the disease evolved and spread.
Food fraud, where different or low-quality food is deliberately mislabelled and sold as high-quality goods, risks the health of consumers as well as the economic viability of producers and manufacturers. To combat this, researchers have figured out that analysing the past and present behaviour of criminal activity could predict what they might target in the future.
The rise of alternative health practices and a quest for purity can partly explain the falling confidence in vaccines which is driving outbreaks of preventable diseases such as measles, according to Heidi Larson, professor of anthropology, risk and decision medicine at the UK’s London School of Hygiene & Tropical Medicine. She is working to understand the causes of vaccine hesitancy in order to devise ways of rebuilding trust.
Some materials are special not for what they contain, but for what they don’t contain. Such is the case with metal-organic frameworks (MOFs) – ultra-porous structures that are being developed for a variety of future applications from fire-proofing to drug-delivery.
Tiny pieces of plastic, now ubiquitous in the marine environment, have long been a cause of concern for their ability to absorb toxic substances and potentially penetrate the food chain. Now scientists are beginning to understand the level of threat posed to life, by gauging the extent of marine accumulation and tracking the movement of these contaminants.
Testing the safety of medicines and chemicals on organ-like structures developed from various types of stem cells could reduce the reliance on animal testing and streamline chemical and drug development, according to scientists in the Netherlands who are in the early stages of developing such technology.
Complex and painful disease has been historically overlooked, researchers say.
Robin Garrity says that registration, identification and geofencing will increase security.
Chemical switches on DNA could explain how the environment may influence the traits we pass on, according to Prof. Thomas Carell.