The successful development of mRNA vaccines for Covid-19 is ‘transformational’ and opens the doors to new types of vaccines for other infectious diseases as well as cancer, according to Dr Özlem Türeci and Dr Uğur Şahin, the co-founders of Germany’s BioNTech.
The speed with which coronavirus vaccines have been developed surprised everyone and could transform public health into the future, says Dr Fergus Sweeney, head of the clinical studies and manufacturing taskforce at the European Medicines Agency (EMA). Here he gives us a glimpse at the work of the regulator over the past year as part of the fight against Covid-19.
A new antibody that can mount a double attack on the Sars-CoV-2 virus by binding to two different sites on the spike protein is starting human trials, leading to hopes of an antibody therapy that can maintain its effectiveness even against new variants of coronavirus.
The earliest signs of alkaptonuria are often subtle and harmless, like a diaper stained black. However, over the years, this rare genetic disease can lead to a lifetime of surgery. Now, after 20 years of research, a not-so-new drug can offer relief for thousands of patients worldwide.
Medical suppliers must change how they manage their supply chains, and factories need to be able to rapidly pivot to manufacturing different products, in order to respond quickly to the next major crisis and avoid shortages of vital medical goods, experts say.
Advances in diagnosis and care have yielded significant improvements in childhood cancer survival rates in Europe, but the long-term side-effect burden in young people — driven by the unlicensed use of adult cancer medicines — often means the price of survival is high, scientists say.
Our pet dogs could help extend human lives beyond their documented effects on people’s wellbeing. Increasingly, studies are looking at how the domestic dog, Canis familiaris, is key to understanding cognition and processes involved in ageing – something that could improve both animal and human wellbeing.
The human immune system is powerful and complex. It must be on guard at all times and be able to distinguish friend from foe. Unfortunately, it does not always get it right and sometimes attacks the body’s own cells, causing hundreds of ‘autoimmune’ diseases, from multiple sclerosis (MS) to rheumatoid arthritis.
A mysterious flu-like illness that caused loss of taste and smell in the late 19th century was probably caused by a coronavirus that still causes the ‘common cold’ in people today, according to Professor Marc Van Ranst at KU Leuven in Belgium, an expert on coronaviruses.
Hyperloops could replace short-haul air travel.
Car manufacturers are rolling out higher levels of automation but public acceptance is lagging behind.
Dr Kate Rychert studies ocean plate structures.