Regenerative medicine takes a different approach to treating disease by aiming to regrow, repair or replace tissues and organs to restore their normal functions instead of just treating symptoms. This month, Horizon takes a deeper look at the promise of this emerging field and takes stock of where we are now. We look at how scientists are beginning human trials of a technique that repurposes cells from one part of the body to treat disorders in another, and find out how 3D printing is helping to tackle arthritis. We also look at the challenges of mass producing the raw materials for regenerative medicine - stem cells - and some of the regulatory and ethical issues that are emerging as the industry develops.
Regenerative medicine should be governed, firstly, by the principle of do no harm, but a better balance between risk and regulation is required to bring innovations to market more quickly, according to Ton Rabelink, professor of internal medicine and head of nephrology at Leiden University in the Netherlands. He says that Europe is in danger of falling behind countries such as Japan and the US if there is not more flexibility in how new therapies are regulated.
Dumped waste, from used nappies to industrial by-products, have long wound up in landfills and can take hundreds of years to decay. In October we speak to the scientists figuring out how to keep such items in use to reduce rubbish and create a so-called circular economy. We learn about new efforts to mine industrial waste for the rare metals that go into making aircraft parts, pacemakers and bicycle gears, and find out about the culture shift needed to develop a zero-waste society. We also speak to the researchers building a biorefinery to turn soiled nappies into fertilisers and raw materials, and look at whether seaweed could become the next plastic.
The model of our universe as expanding at an accelerated rate has given rise to theoretical constructs such as dark energy and dark matter, which scientists believe could make up 95% of the universe. In September, Horizon takes a deeper look at what we really know about the expanding universe. We speak to Prof. Subir Sarkar, who believes that the Nobel-winning discovery that universe expansion acceleration could be a fluke, and the scientists who are trying to answer the question by allowing us to better measure the expansion rate. We also look at the significance of accurately measuring gravity in deep space, and what dark matter haloes can tell us about the existence of dark energy.
To avoid climate breakdown, eliminating fossil fuels is the easy part, according to Professor Johan Rockström, co-director of the Potsdam Institute for Climate Impact Research in Germany. He says that safeguarding biological resources such as water, soil and biodiversity will be the ultimate test of whether global warming targets can be reached.
As wind turbines become increasingly familiar sights along shorelines, developers of offshore floating platforms, which harness the powerful winds further out to sea, are seeking to establish their technologies as a major viable source of clean energy.
Climate expert says real challenge is safeguarding biological resources.
Floating wind turbines could be a clean energy game changer.
A circular economy needs new business models and reusable products, says Felipe Maya.