Regenerative medicine takes a different approach to treating disease by aiming to regrow, repair or replace tissues and organs to restore their normal functions instead of just treating symptoms. This month, Horizon takes a deeper look at the promise of this emerging field and takes stock of where we are now. We look at how scientists are beginning human trials of a technique that repurposes cells from one part of the body to treat disorders in another, and find out how 3D printing is helping to tackle arthritis. We also look at the challenges of mass producing the raw materials for regenerative medicine - stem cells - and some of the regulatory and ethical issues that are emerging as the industry develops.
Regenerative medicine should be governed, firstly, by the principle of do no harm, but a better balance between risk and regulation is required to bring innovations to market more quickly, according to Ton Rabelink, professor of internal medicine and head of nephrology at Leiden University in the Netherlands. He says that Europe is in danger of falling behind countries such as Japan and the US if there is not more flexibility in how new therapies are regulated.
Fifty years after humans first set foot on the moon, Earth’s only permanent natural satellite is back in the news with China’s successful landing on the moon’s as-yet-unexplored far side. This month, Horizon looks at how Europe is contributing to moon research. We hear from the European Space Agency’s director of human and robotic exploration about their plans to send a robot and then humans to the lunar surface in the 2020s, and speak to the scientists trying to fill the holes in our understanding of how the moon was formed. We also hear how we could solve the puzzle of where water on Earth originated by analysing volatile substances from the moon, and take a look at the methods and facilities being developed to protect precious extra-terrestrial samples from human contamination.
The languages we speak and how we speak them are an integral part of our identity, shaping not only how we see the world but also how people see us. In January, Horizon puts language under the spotlight, kicking off the month with a look at Europe’s minority languages and how to preserve them. We also delve into the social and cognitive aspects of language use, finding out how accents arise and how they affect people’s perception of the speaker, and discovering how ageing affects linguistic capacity in bilingual people – and vice versa. We also speak to researchers looking into the language impairment dyslexia and potential options for early diagnosis.
A study in mice has indicated that the make-up of bacteria in the gut is linked with learning abilities and memory, providing a potential avenue of research into how to maintain cognitive functioning as we age.
Scientists are investigating the link between gut bacteria and ageing.
Their ageing rates might teach us how to grow old gracefully, too.
We are entering a second era of lunar exploration, says ESA’s Dr David Parker.