As the clocks go back this October, Horizon takes a moment to look at the 24-hour rhythms that govern life. We talk to scientists trying to alter the internal clocks of our cells to help fight obesity and diabetes, and others working out the best time for each patient to take medicines. We also learn how tobacco plants can change their body clocks in a last-ditch attempt to survive when they’re threatened by predators or food scarcity.
The anti-tumour properties of chemotherapy drugs could work twice as well if you take them at times when the body is most receptive, but that means different timetables for different people, according to researchers working to understand how to use the body’s daily rhythms to make medicine optimally effective and reduce unpleasant side effects.
Sleeping, eating and even going to the bathroom, our bodies are clearly affected by the time of day. But the cycle of the moon could also have impacts on our biological functions, according to Professor Kristin Teßmar-Raible, at the Max F. Perutz Laboratories, University of Vienna, Austria, who is leading LUNAR.CLOCK, a project funded by the EU's European Research Council exploring how the moon affects marine organisms.
Keeping calorie-burning brown fat cells running throughout the day rather than allowing them to switch on and off, possibly via tablets or injections, could help our bodies cope better with a modern day abundance of food, according to researchers who are investigating the link between the body clock and obesity.
Plants can override their own body clocks in times of stress, hijacking their programmed activities in a last-ditch attempt to survive, according to researchers who believe their work could change the way we think about internal timing.
From alternative currencies in Limburg to virus-hunters tracking down the next pandemic, there’s plenty of cutting-edge research and innovation in Belgium. For the open day of European institutions in Brussels, Horizon has gone into its archives and pulled together a list of its top articles featuring scientists in the northern European country.
How will we have enough food to feed another 2 billion people by the middle of this century without destroying our planet? Agriculture is already one of the biggest contributors to climate change. This month, we hear from scientists designing disease-resistant crops using gene editing, packing more calcium into finger millet, and resurrecting ancient crop varieties to offset the sector’s environmental impact. Plus, we hear from Dr Manoj Dora about so-called lean agriculture, which is looking to make agriculture more sustainable by eliminating waste from the production process.
An on-demand style of farming inspired by the Toyota car manufacturing lines of the 1950s could be the key to improving efficiency on farms, which would in turn lead to cheaper food in European supermarkets, according to Dr Manoj Dora from Brunel University London in the UK.
For most women, the first pregnancy is a joyous time that they will remember with tenderness for the rest of their lives. But for 5 % of all pregnant women around the world, the journey towards childbirth takes an unexpected turn for the worse.
‘Lean’ farming could reduce waste.
Pre-eclampsia affects 800 000 women a year worldwide.
SESAME co-founder helped set up Middle East particle accelerator to build bridges in the region.