As the clocks go back this October, Horizon takes a moment to look at the 24-hour rhythms that govern life. We talk to scientists trying to alter the internal clocks of our cells to help fight obesity and diabetes, and others working out the best time for each patient to take medicines. We also learn how tobacco plants can change their body clocks in a last-ditch attempt to survive when they’re threatened by predators or food scarcity.
The anti-tumour properties of chemotherapy drugs could work twice as well if you take them at times when the body is most receptive, but that means different timetables for different people, according to researchers working to understand how to use the body’s daily rhythms to make medicine optimally effective and reduce unpleasant side effects.
Sleeping, eating and even going to the bathroom, our bodies are clearly affected by the time of day. But the cycle of the moon could also have impacts on our biological functions, according to Professor Kristin Teßmar-Raible, at the Max F. Perutz Laboratories, University of Vienna, Austria, who is leading LUNAR.CLOCK, a project funded by the EU's European Research Council exploring how the moon affects marine organisms.
Keeping calorie-burning brown fat cells running throughout the day rather than allowing them to switch on and off, possibly via tablets or injections, could help our bodies cope better with a modern day abundance of food, according to researchers who are investigating the link between the body clock and obesity.
Plants can override their own body clocks in times of stress, hijacking their programmed activities in a last-ditch attempt to survive, according to researchers who believe their work could change the way we think about internal timing.
The world looks very different from this time last year. The coronavirus pandemic has highlighted the centrality of science, research and innovation, accelerated some changes already in the works, but also exposed our weaknesses. In September, Horizon looks at how the pandemic is reshaping Europe in areas including health research, work, tech, transport and food – and how research can contribute to Europe’s recovery over the coming years. We will also be covering the European Research & Innovation Days at the end of the month, which will bring together scientists, policymakers, entrepreneurs and citizens to debate how research and innovation can ensure that the transition to a post-coronavirus society is sustainable, inclusive and resilient.
In August, Horizon looks at one of the features that makes Earth unique and habitable: plate tectonics. We explore what we know – and still don’t know – about how the shifting plates beneath our feet shape our planet. We speak to researcher Dr Kate Rychert, who wants to understand what makes a plate plate-like, and delve into one of the outstanding mysteries in the subject – how and why plate tectonics began. We find out about the link between mountain formation, erosion and climate change, and we look at what moonquakes and marsquakes can reveal about tectonic activity elsewhere.
European governments need to provide investment on a ‘wartime footing’ to stimulate a post-coronavirus economic recovery, but also need to redefine economic success to incorporate climate and social goals, the European Research and Innovation Days conference has heard.
The Covid-19 crisis provides an opportunity to reshape Europe’s economy, conference heard.
'Frontier research' scientists share how they are fighting Covid-19.
Dr Kate Rychert studies ocean plate structures.